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    ERC Consolidator Grant to combine synthetic biology with infection biology

    November 28 2017

    Today the ERC announced this years' consolidator grant winners and our lab is one of them!

    The project will use innovative approaches for infection biology by combining synthetic biology and quantitative single cell biology including single cell RNA-seq, CRISPRi, engineered bistable switches and microfluidics. We will try to reveal the molecular mechanisms underlying cell-to-cell variability and its importance in virulence and antibiotic resistance.

    Initially, we are looking for 2 PhD students and a technician but applications for post-doc positions are also welcome. The start date is flexible but not before November 2018. Useful skills and interests are in single cell biology, infection biology, computational biology, bioinformatics or synthetic biology. But generally, all creative people should send an inquiry to the lab.

    Lab retreat 2017 Budapest

    November 20 2017

    Our lab retreat to Budapest was a great succes! Friday was spent doing a SWOT analysis and coming up with a mission statement for the lab. There was also time to visit the beautiful city and try the local cuisine. We also happended to stumble into an amazing pub named Szimpla where the team became creative (see picture).

    Learning new tricks

    October 27 2017

    This week Vladimir and Jan-Willem went to visit Roi Avraham at the Weizmann Institute in Israel to learn all about preparing libraries for sequencing. We learned a lot, setup an exciting collaboration and will definitely come back to see more of the country.

    Preprint now published in Nature Communications

    October 09 2017

    Our preprint in BioRxiv combining experiments with modeling to understand competence regulation is now out in Nature Communications.

    Congratulations to Stefany, Robin, Arnau, Morten! This has been a great collaboration with Sander van Doorn and Franjo Weissing at GELIFES.

    For some background on the work, see the 'Behind the paper': Synchronizing bacterial sex.

    ScienceLinx also did an interview with SanderHow does a bacterium make sense of the world?

    Welcome to MSc student Pascal!

    October 02 2017

    Today Pascal Roth started his 'first step' Masters project (3 months) in our lab, testing different CRISPR systems, under the supervision of Dimitra. Good luck!

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    Research

    The Veening lab is interested in understanding fundamental processes in the pneumococcus with the long-term goal to come up with new strategies to prevent and treat pneumococcal infections.

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    Teaching

    We host BSc and MSc students for their lab rotations, are involved in various practical workshops and teach in several undergraduate courses.

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    Alumni

    Meet our former team members here.

     

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    Resources

    You can find links to most of our data here, our collaborators, as well as our Addgene and BGSC pages. Also, see some useful pages for things to do around Lausanne.

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    Join Us!

    We are always interested in motivated people. So contact us for possibilities to work in the lab!

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    Contact

    How to find us, contact us and send stuff to us.

     

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    Jan-Willem Veening

    Group leader

    Rieza Aprianto

    PhD candidate

    Afonso Bravo

    PhD candidate

    Arnau Domenech

    Post-doc

    Clement Gallay

    PhD candidate

    Paddy Gibson

    PhD candidate

    Lance Keller

    Post-doc

    Jun Kurushima

    Post-doc

    Xue Liu

    Post-doc

    Renske van Raaphorst

    PhD candidate

    Stefano Sanselicio

    Post-doc

    Jelle Slager

    PhD candidate

    Dimitra Synefiaridou

    PhD candidate

    Anne-Stéphanie Rueff

    Post-doc

    Pascal Roth

    First step MSc student
    Jan-Willem Veening
    Group leader
    Rieza Aprianto
    PhD candidate
    Afonso Bravo
    PhD candidate
    Arnau Domenech
    Post-doc
    Clement Gallay
    PhD candidate
    Paddy Gibson
    PhD candidate
    Lance Keller
    Post-doc
    Jun Kurushima
    Post-doc
    Xue Liu
    Post-doc
    Renske van Raaphorst
    PhD candidate
    Stefano Sanselicio
    Post-doc
    Jelle Slager
    PhD candidate
    Dimitra Synefiaridou
    PhD candidate
    Anne-Stéphanie Rueff
    Post-doc
    Pascal Roth
    First step MSc student

    Latest publications

    Quorum sensing integrates environmental cues, cell density and cell history to control bacterial competence.

    Moreno-Gámez S, Sorg RA, Domenech A, Kjos M, Weissing FJ, van Doorn GS, Veening JW.

    Nat Commun. 2017 Oct 11. 10.1038/s41467-017-00903-y

    Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria.

    Veening JW, Blokesch M.

    Nat Rev Microbiol. 2017 Oct. 10.1038/nrmicro.2017.66

    Chromosome segregation drives division site selection in Streptococcus pneumoniae.

    van Raaphorst R, Kjos M, Veening JW.

    Proc Natl Acad Sci U S A. 2017 Jul 18. 10.1073/pnas.1620608114