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    Welcome to new PhD candidate Vincent de Bakker!

    January 10 2019

    This week we welcome Vincent to our team! Vincent will be working within the framework of a recently approved JPIAMR (Joint Program Initiative on antimicrobial resistance) project called DISRUPT where he will identify targets and mode of action of novel anti-biofilm agents in S. pneumoniae and S. aureus using a combination of high-throughput screens and computational analysis.

     

     

    Congratulations to Dimi!

    December 19 2018

    Congratulations to Dimitra for passing her mid-thesis exam! Thanks to Yolanda Schaerli and Tim van Opijnen for doing excellent jury work. Cheers!

    New preprint: Refining the pneumococcal competence regulon

    December 15 2018

    Previous studies on the competence regulon were performed with microarray technology and limited to an incomplete set of known genes. Using RNA-sequencing, combined with an up-to-date genome annotation, Jelle and Rieza provide an updated overview of competence-regulated genes, encompassing refinement of the regulons of ComE, BlpR and ComX, as well as the stress response CiaR and VraR (LiaR) regulons. Read the preprint on BioRxiv here.

    Our latest work on the cover of Cell Reports!

    November 27 2018

    Our work (Arnau & Jelle's) on the identification of a new (3rd) mechanism by which certain antibiotics induce pneumococcal competence for DNA uptake on the cover of Cell Reports!

    Drugs targeting PBP3 promote chain formation. Cell chains retain, rather than diffuse, the quorum-sensing peptide CSP. Chaining populations feature a longer competence and transformation time window.

    Here is the link to the paper

    See a general audience write up on our work from the University of Lausanne here (in French) 'Le pneumocoque ou l’art de déjouer les antibiotiques'

    And for a nice interview with Jelle (in Dutch and English) 'Hoe antibiotica helpen bij verspreiden van resistentie', click here

    New transnational JPIAMR grant awarded!

    November 12 2018

    Our JPIAMR (Joint Program Initiative on Antimicrobial Resistance) proposal entitled DISRUPT was selected for funding! Out of 104 applications, 10 were selected for funding. Read more here: https://www.jpiamr.eu/6th-jpiamr-joint-call-results/

    DISRUPT is coordinated by former Veeninglab post-doc Morten Kjos (now associate professor at the Norwegian University of Life Sciences) and, besides our lab, includes the teams of Nassos Typas and Christophe Merten, both from the EMBL in Heidelberg.

    The idea of DISRUPT is to fight antimicrobial resistant infections by high-throughput discovery of biofilm-disrupting agents and mechanisms. The project will start in 2019 and our lab will be funded via the SNF.

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    Research

    The Veening lab is interested in understanding fundamental processes in the pneumococcus with the long-term goal to come up with new strategies to prevent and treat pneumococcal infections.

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    Teaching

    We host BSc and MSc students for their lab rotations, are involved in various practical workshops and teach in several undergraduate courses.

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    Alumni

    Meet our former team members here.

     

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    Resources

    • You can find links to most of our data here, our collaborators, as well as our Addgene and BGSC pages. Also, see some useful pages for things to do around Lausanne.
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    Join Us!

    We are always interested in motivated people. So contact us for possibilities to work in the lab!

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    Contact

    How to find us, contact us and send stuff to us.

     

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    Job openings

    We are hiring!

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    Equipment

    Equipment and facilities available for the Veening lab.

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    Jan-Willem Veening

    Group leader

    Rieza Aprianto

    Post-doc

    Vincent de Bakker

    PhD candidate

    Afonso Bravo

    PhD candidate

    Julien Denereaz

    MSc student

    Arnau Domenech

    Post-doc

    Clement Gallay

    PhD candidate

    Paddy Gibson

    PhD candidate

    Lance Keller

    Post-doc

    Jun Kurushima

    Post-doc

    Xue Liu

    Post-doc

    Renske van Raaphorst

    PhD candidate

    Monica Rengifo Gonzalez

    Lab manager

    Anne-St├ęphanie Rueff

    Post-doc

    Stefano Sanselicio

    Post-doc

    Dimitra Synefiaridou

    PhD candidate

    Vishwachi Tripathi

    MSc student

    Putri Utari

    Post-doc

    Alice Wallef

    MSc student
    Jan-Willem Veening
    Group leader
    Rieza Aprianto
    Post-doc
    Vincent de Bakker
    PhD candidate
    Afonso Bravo
    PhD candidate
    Julien Denereaz
    MSc student
    Arnau Domenech
    Post-doc
    Clement Gallay
    PhD candidate
    Paddy Gibson
    PhD candidate
    Lance Keller
    Post-doc
    Jun Kurushima
    Post-doc
    Xue Liu
    Post-doc
    Renske van Raaphorst
    PhD candidate
    Monica Rengifo Gonzalez
    Lab manager
    Anne-St├ęphanie Rueff
    Post-doc
    Stefano Sanselicio
    Post-doc
    Dimitra Synefiaridou
    PhD candidate
    Vishwachi Tripathi
    MSc student
    Putri Utari
    Post-doc
    Alice Wallef
    MSc student